Eur J Musculoskel Dis 2022 Jan-Apr;11(1):35-39
LETTER TO THE EDITOR
OLLIER’S DISEASE
V. Sollazzo
Medical Director, Medical Centre, Ferrara, Italy
Correspondence to:
Vincenzo Sollazzo MD,
Orthopedic Surgeon, Medical Director, Medical Center,
Ferrara, Italy
e-mail: slv@unife.it
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Received: 06 October, 2021
Copyright: |
ISSN: 2038-4106 This publication and/or article is for individual use only and may not be further reproduced without written permission from the copyright holder. Unauthorized reproduction may result in financial and other penalties. Disclosure: All authors report no conflicts of interest relevant to this article.
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ABSTRACT
Spranger type 1 is a rare bone condition known as Ollier’s disease (OD). It is characterized by numerous enchondromatosis with a distinctive asymmetrical arrangement. This illness affects only the appendicular bones. There is a lack of complete comprehension of the pathophysiology of enchondromatosis. Several publications have recently proposed that heterozygous mutations in the PTHR1, IDH1, and IDH2 genes can cause OD. Phalanges and metacarpals are the bone structures most frequently affected by multiple enchondromas. OD is characterized by asymmetrical osteolytic lesions that have well-defined sclerotic edges when viewed through the lens of radiology. Even though the therapy is conservative in the vast majority of cases, numerous potential treatment alternatives for challenging patients are explored.
KEYWORDS: Ollier’s disease, enchondromatosis, hyaline, cartilage, bone
