Eur J Musculoskel Dis 2022 Sept-Dec;11(3):133-137
LETTER TO THE EDITOR
MOLECULAR MECHANISM OF SARCOLEMMA DISEASE: A SHORT REVIEW
V. Candotto1 and P. Carls2
1Lecturer, Dental School, Albanian University, Tirana, Albania
2Consultant Oral-Maxillofacial Surgeon, 69 Banbury Road, Oxford, UK
Correspondence to:
Valentina Candotto, MD
Lecturer,
Dental School,
Albanian University,
Tirana, Albania
e-mail: candottovalentina@gmail.com
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Received: 23 October, 2022 Copyright: |
ISSN: 2038-4106 This publication and/or article is for individual use only and may not be further reproduced without written permission from the copyright holder. Unauthorized reproduction may result in financial and other penalties. Disclosure: All authors report no conflicts of interest relevant to this article. |
ABSTRACT
Genetic mutations expressing components of the dystrophin-glycoprotein complex (that attaches cytoskeleton to cell membrane, the sarcolemma) can cause several muscular dystrophies. This short literature review has been conducted to assess the molecular basis of possible mechanisms and factors which affect sarcolemma and result in muscular dystrophies. A better knowledge of mechanisms that improve sarcolemma repair could lead to new therapeutic targets in treating muscular dystrophy.
KEYWORDS: Sarcolemma, cell, muscle, disease, apparatus
