Eur J Musculoskel Dis 2022 Jan-Apr;11(1):11-14
REVIEW
DENTINOGENESIS IMPERFECTA: A REVIEW
F. Carinci
Department of Translational Medicine, University of Ferrara, Ferrara, Italy
Correspondance to:
Prof. Francesco Carinci
Department of Translational Medicine, University of Ferrara, Ferrara, Italy
e-mail: crc@unife.it
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Received: 07 March, 2022
Copyright: |
ISSN: 2038-4106 This publication and/or article is for individual use only and may not be further reproduced without written permission from the copyright holder. Unauthorized reproduction may result in financial and other penalties. Disclosure: All authors report no conflicts of interest relevant to this article.
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ABSTRACT
Dentinogenesis imperfecta (DGI) is an inherited dentin disease resulting in fragile teeth that affects the primary and permanent dentitions. It causes physical and aesthetic problems, including tooth discoloration and staining, and is responsible for great damage and wear to the entire dentition. DGI is classified into three types, with COL1A1 and COL1A2 gene mutations present in the first type, and mutations of the DSPP gene presenting in the second and third type. Treatment is focused on restoration and replacement of damaged and worn teeth, as well as aesthetic improvements. Restorative, prosthodontic, and orthodontic treatment is often necessary. The aim of this paper is to shed light on this pathological disease and the importance of obtaining an early diagnosis which is necessary to implement treatment.
Keywords: DGI, dentin defect, dental, musculoskeletal
